Alzheimer’s malady is a degenerative affliction of the nervous system that typically commences surreptitiously and advances gradually. It stands as the preeminent manifestation of dementia. Patients predominantly manifest with a progressive descent in memory, linguistic and visuospatial faculties, and deterioration in daily living competencies, oftentimes concomitant with psychiatric manifestations.
The malady is engendered by a confluence of genetic and environmental elements and principally afflicts individuals beyond the age of 60.
When the elderly domiciled exhibit nascent indications of ailment, they ought to promptly pursue medical intervention for timely prophylaxis and premature therapeutics.
How to mitigate the jeopardy of ailment?
Despite novel pharmaceuticals demonstrating efficacy in decelerating the malady’s progression, it is imperative to note the current dearth of a panacea for Alzheimer’s. Consequently, preventive measures assume paramount significance. A burgeoning body of research substantiates the preventability of Alzheimer’s, akin to other protracted maladies.
Myriad risk factors can augment the predisposition to Alzheimer’s. Advanced age, particularly beyond 65 years, the female gender, susceptibility to or genetic mutations predisposing one to Alzheimer’s, and familial antecedents of the malady, accentuate the vulnerability to its onset.
Age, gender, genetics, among others, are immutable factors. Nonetheless, a plethora of modifiable risk factors can be ameliorated, such as sedentary lifestyle, tobacco consumption, immoderate alcohol intake, paucity of social interaction, corpulence, elevated blood pressure, diabetes, despondency, and auditory impairment.
The International Guidelines for the Evidence-Based Prevention of Alzheimer’s Disease posit that adherence to the ensuing precepts is anticipated to defer or forestall 40% of Alzheimer’s incidence.
1. Sustain a salubrious lifestyle
Eschew corpulence in youth and middle age, and eschew emaciation in senescence (beyond 65 years); pursue maximal education in the nascent years; engage in cognitively stimulating activities; persevere in regular physical exertion; refrain from smoking and circumvent exposure to second-hand smoke; uphold sound sleep hygiene and promptly address sleep anomalies.
2. Avert maladies heightening Alzheimer’s jeopardy
Vigilantly monitor cognitive function in hypertensive and diabetic patients; safeguard against cranial trauma; uphold mental well-being; closely monitor cognitive function in individuals with depression; evade cerebrovascular maladies, with vigilant cognitive surveillance in stroke patients; foster cardiovascular health, actively treating atrial fibrillation in patients; regularly assess blood homocysteine levels, with proactive management in cases of hyperhomocysteinemia.
Furthermore, maintaining robust physical health is imperative, with vigilant cognitive monitoring in individuals with frailty; cultivate relaxation and sidestep excessive stress; and incorporate dietary vitamin C or supplements for cognitive fortification.