How to Use 3-Mercaptopropyltrimethoxysilane (MPTMS) for Various Applications

If you are looking for a versatile and efficient organosilane reagent, you might want to consider 3-mercaptopropyltrimethoxysilane (MPTMS), also known as 3-(trimethoxysilyl)-1-propanethiol. This compound has a thiol group that can react with various substrates and a trimethoxysilyl group that can form stable bonds with silica or other metal oxides. In this article, we will introduce some of the applications and benefits of using MPTMS for different purposes.

What is MPTMS?

MPTMS is a colorless liquid with a molecular weight of 196.34 and a CAS number of 4420-74-0. It has a boiling point of 213-215 °C and a density of 1.057 g/mL at 25 °C. It is soluble in water and most organic solvents, such as ethanol, acetone, and toluene.

MPTMS can be used as a precursor for silica or as a coupling agent for various materials. It can form self-assembled monolayers (SAMs) on metal surfaces, such as gold, silver, or copper, by forming thiolate bonds. It can also react with hydroxyl groups on silica or other metal oxides, such as TiO2, CeO2, or La2O3, by forming siloxane bonds. These bonds can improve the adhesion, corrosion resistance, and surface modification of the substrates.

What are the applications of MPTMS?

MPTMS has been used for various applications in different fields, such as nanotechnology, catalysis, biotechnology, and environmental engineering. Here are some examples:

  • MPTMS can be used to immobilize nanoparticles on metal electrodes or substrates. For instance, MPTMS can form a bilayer with multiwalled carbon nanotubes (MWNTs) on gold electrodes, which can be used to study the electrochemical properties of fluphenazine.
  • MPTMS can be used to synthesize polyorganosiloxane nanoparticles from MPTMS and other monomers by photoinitiated thiol-ene polymerization. These nanoparticles can be used to prepare nanocomposite films with enhanced mechanical and thermal properties.
  • MPTMS can be used to modify the surface of berea sandstone with silica nanofluid (NF) to improve the enhanced oil recovery (EOR) area in the petroleum industry. The MPTMS-SiO2 NF can increase the wettability and permeability of the sandstone and reduce the interfacial tension between oil and water.
  • MPTMS can be used to form composites with kaolin, which can be used as an adsorbent for the removal of heavy metals from wastewater. The MPTMS-kaolin composites can exhibit high adsorption capacity and selectivity for Cu(II), Pb(II), and Cd(II) ions.

What are the benefits of using MPTMS?

MPTMS has several advantages over other organosilanes, such as:

  • MPTMS has a higher reactivity and stability than other thiols, such as mercaptoethanol or mercaptopropionic acid.
  • MPTMS has a lower toxicity and environmental impact than other organosilanes, such as chlorosilanes or alkoxysilanes.
  • MPTMS has a lower cost and higher availability than other organosilanes, such as vinylsilanes or epoxysilanes.

How to buy MPTMS?

If you are interested in buying MPTMS for your research or industrial needs, you can find it from various suppliers online or offline. However, you should pay attention to the quality, purity, and price of the product before making a purchase. You should also check the safety data sheet (SDS) and certificate of analysis (COA) of the product to ensure its proper handling and storage.

One of the reliable and reputable suppliers of MPTMS is Pengrun New Materials, which offers MPTMS with 95% purity and competitive pricing. You can order MPTMS from Pengrun online or by phone, fax, or email. You can also request a quote or a sample of the product from their website.


MPTMS is a versatile and efficient organosilane reagent that can be used for various applications and benefits. It can form stable and functional bonds with silica or other metal oxides, as well as with metal surfaces. It can be used to synthesize, modify, or immobilize various materials, such as nanoparticles, polymers, sandstone, or kaolin. It has a higher reactivity, stability, and availability than other organosilanes, and a lower toxicity and environmental impact. If you are looking for a high-quality and affordable source of MPTMS, you can consider Shandong Pengrun New Materials Co Ltd as your supplier.

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